Acta Chir Orthop Traumatol Cech. 2017; 84(5):391-395 | DOI: 10.55095/achot2017/059
Chirurgické léčení syndromu karpálního tunelu - je antiadhezivní gel efektivní?Původní práce
- 1 Kafkas Univercity, Department of Orthopedics and Traumatology, Faculty of Medicine, Kars, Turkey
- 2 Kafkas Univercity, Department of Anesthesiology and Reanimation, Faculty of Medicine, Kars, Turkey
- 3 Metin Sabanci Baltalimani Bone Diseases Training and Research Hospital, Department of Orthopedics and Traumatology, İstanbul, Turkey
PURPOSE OF THE STUDY:
The purpose of the current study is to assess the efficacy of anti-adhesion gel on the symptom severity and functional outcomes after mini incision open surgery for carpal tunnel syndrom (CTS).
MATERIAL AND METHODS:
A total of 200 CTS patients (154 women, 46 men) were included in this study. Group I (n = 100; 78 women, 22 men) did not receive local administration of anti-adhesion gel, while anti-adhesion gel consisting of hyaluronic acid-carboxy-methylcellulose (Seprafilm®, SanofiBiosurgery, Bridgewater, NJ, USA) was locally applied to patients in Group II (n = 100; 76 women, 24 men). All patients recruited in this study had received conservative treatment comprised of non-steroidal anti-inflammatory drugs, steroid injection, replacement of vitamin B and stabilization with splints. Cases that did not benefit from these therapeutic options during one year were assigned as candidates for surgical treatment.
RESULTS:
There was no significant difference between two groups in terms of mean age, gender distribution, preoperative and postoperative Boston questionnaire (BQ) scores, difference of BQ scores after the operation, and the presence of the disease on the left or right side. According to postoperative 1. Year results, there was no significant difference between two groups.
CONCLUSIONS:
Results of the current study demonstrated that use of anti-adhesion gel during mini incision open surgery for CTS did not bring about significant advantages in terms of functional or symptomatic outcomes. Further, controlled trials on larger series are warranted to understand the beneficial effects of anti-adhesive materials during the surgical treatment of CTS.
Klíčová slova: anti-adhesion gel, Boston questionnaire, carpal tunnel syndrome
Zveřejněno: 1. říjen 2017 Zobrazit citaci
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Reference
- Adanali G, Verdi M, Tuncel A, Erdogan B, Kargi E. Effects of hyaluronic acid-carboxymethylcellulose membrane on extraneural adhesion formation and peripheral nerve regeneration. J Reconstr Microsurg. 2003;19:29-36.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Brown RA, Gelberman RH, Seiler JG 3rd, Abrahamsson SO. Carpal tunnel release: a prospective, randomized assessment of open and endoscopic methods. J Bone Joint Surg Am. 1993;75:1265-1275.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Chammas M, Boretto J, Burmann LM, Ramos RM, Neto FS, Silva JB. Carpal tunnel syndrome - Part II (treatment). Rev Bras Orthop. 2014;49:437-445.
Přejít k původnímu zdroji...
- Cranford CS, Ho JY, Kalainov DM, Hartigan BJ. Carpal tunnel syndrome. J Am Acad Orthop Surg. 2007;15:537-548.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Greenslade JR, Mehta RL, Belward P, Warwick DJ. Dash and Boston questionnaire assessment of carpal tunnel syndrome outcome: what is the responsiveness of an outcome questionnaire? J Hand Surg Br. 2004;29:159-164.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Keith MW, Masear V, Amadio PC, Andary M, Barth RW, Graham B, Chung K, Maupin K, Watters WC 3rd, Haralson RH 3rd, Turkelson CM, Wies JL, McGowan R.. Treatment of carpal tunnel syndrome. J Am Acad Orthop Surg. 2009;17:397-405.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Keramettin A, Cengiz C, Nilgun C, Ayhan B. Microsurgical open mini uniskin incision technique in the surgical treatment of carpal tunnel syndrome. Neurol India. 2006;54:64-67.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Levine DW, Simmons BP, Koris MJ, Daltroy LH, Hohl GG, Fossel AH, Katz JN. A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome. J Bone Joint Surg Am. 1993;75:1585-1592.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Magill CK, Tuffaha SH, Yee A, Luciano JP, Hunter DA et al. The short- and long-term effects of Seprafilm on peripheral nerves: a histological and functional study. J Reconstr Microsurg. 2009;25:345-354.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Murthy PG, Goljan P, Mendez G, Jacoby SM, Shin EK, Osterman AL. Mini-open versus extended open release for severe carpal tunnel syndrome. Hand (NY). 2015;10:34-39.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Park JS, Lee JH, Han CS, Chung DW, Kim GY. Effect of hyaluronic acid-carboxymethylcellulose solution on perineural scar formation after sciatic nerve repair in rats. Clin Orthop Surg. 2011;3:315-324.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Petersen J, Russell L, Andrus K, MacKinnon M, Silver J, Kliot M. Reduction of extraneural scarring by ADCON-T/N after surgical intervention. Neurosurgery. 1996;38:976-983.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Siemionow M, Uygur S, Ozturk C, Siemionow K. Techniques and materials for enhancement of peripheral nerve regeneration: a literatüre review. Microsurgery. 2013;33:318-328.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Stevens JC. AAEM minimonograph #26: the electrodiagnosis of carpal tunnel syndrome. American Association of Electrodiagnostic Medicine. Muscle Nerve. 1997;20:1477-1486.
Přejít k původnímu zdroji...
- Thoma A, Veltri K, Haines T, Duku E. A systematic review of reviews comparing effectiveness of endoscopic and open carpal tunnel decompression. Plast Reconstr Surg. 2004;113:1184-1191.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Tung TH, Mackinnon SE. Secondary carpal tunnel surgery. Plast Reconstr Surg. 2001;107:1830-1843.
Přejít k původnímu zdroji...
- Weigel PH, Fuller GM, LeBoeuf RD. A model for the role of hyaluronic acid and fibrin in the early events during the inflammatory response and wound healing. J Theor Biol. 1986;119:219-234.
Přejít k původnímu zdroji...
Přejít na PubMed...
- Winterton RIS, Farnell R. Peripheral nerve entrapment syndromes of the upper limb. Surgery. 2013;31:172-176.
Přejít k původnímu zdroji...